Neither the diagnosis of cases of SARS-CoV-2 nor the detection of environmental contamination by the virus is yet straightforward. Complicated molecular amplification techniques, which require extensive infrastructure and biosafety procedures, prevent people from knowing whether the virus is actually present in their environment.<\/p>\n
The \u201cDo-It-Together SARS CoV-2 Detective\u201d project (more information here<\/a>) will develop a strategy similar to that used for the \u201cGMO Detective<\/a>\u201cThis is the only way to detect the virus responsible for Covid-19. The #CoronaDetective is expected to be highly specific, not only without complicated equipment, but also with a simple +\/- reading. In addition, controls to ensure sensitive detection, with no false positives or negatives, are intrinsic to this solution. The final product, tube strips with dry reagents, could be easily supplied anywhere, without dependence on the cold chain; and monitoring tests could be carried out by ordinary people, with no training in medicine or biology, just a certain ability to follow simple instructions and common sense. In the future, the project will try out \u201cmultiplexed\u201d fluorescent detection, using an inexpensive (even DIY) detector, but with a partner project<\/a> (Slack #proj-neb-lamp-test), it would also be nice to find out whether a simpler color change reaction will be sufficient to obtain valid results.<\/p>\n Human or clinical samples should only be analyzed in environments with access to appropriate biosafety facilities, of course. This project is fully compliant with the OpenCovid-19 initiative's biosafety and biosecurity guidelines, and is fortunate to have appropriate laboratories for all levels of validation. Thanks to freely available information, targeted regions of the virus have already been analyzed, and one has even proved identifiable by team members using these molecular techniques. Our aim now is to optimize the components and develop a validated method that can be used by everyone.<\/p>\n This project is part of the\u2019OpenCovid19 JOGL initiative<\/a>, which aims to collectively develop free, inexpensive, safe and easy-to-use tools and methodologies to combat the COVID-19 pandemic, and is being developed as part of the Covid19 Diagnostic and Detection Challenge<\/a>. It was recently funded by the first wave of beneficiaries of the JOGL open peer-review micro-grant scheme. Everyone can play a part!<\/p>\n Together, open participatory research can help solve today's problems! We welcome your help!<\/strong><\/p>\n You can reach us via this Slack channel: #proj-nucleic-acid-amplification of<\/strong> l\u2019initiative<\/a> JOGL Open Covid-19<\/a>. All this is discussed in : #proj-nucleic-acid-amplification, and <\/strong>more in #chlg-detection-diagnosis. <\/strong>Related work on different RNA extraction methods can be found in: #proj-nucleic-acid-amplification : #proj-rna-extraction.<\/strong><\/p>\n Further work is underway to produce and test open source versions of the enzymes needed in #proj-enzyme-production #freegenes, <\/strong>which are linked to : https:\/\/openbioeconomy.org\/projects\/open-enzyme-collections\/<\/u><\/a> and <\/strong> https:\/\/biobricks.org\/freegenes\/<\/u><\/a><\/strong><\/p>\n Ali Bektas, a collaborator at the Oakland Genomics Center in California, is actively trying to put it all together in a small cartridge, see https:\/\/app.jogl.io\/project\/187<\/u><\/a>.<\/u> Other people are also working on similar methods https:\/\/app.jogl.io\/project\/163<\/u><\/a>. These two projects were also funded by the first wave of beneficiaries of the JOGL open peer-review micro-grant scheme.<\/p>","protected":false},"excerpt":{"rendered":" A project by Guy Aidelberg and colleagues gets micro-funding via JOGL platform<\/p>","protected":false},"author":5,"featured_media":272,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"categories":[20],"tags":[],"class_list":["post-271","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rd"],"acf":[],"meta_box":[],"_links":{"self":[{"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/posts\/271","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/comments?post=271"}],"version-history":[{"count":0,"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/posts\/271\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/media\/272"}],"wp:attachment":[{"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/media?parent=271"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/categories?post=271"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.learningplanetinstitute.org\/en\/wp-json\/wp\/v2\/tags?post=271"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}How to contribute<\/h3>\n